Pathology · single question
Continuing the previous case (punched-out jaw lesions): which cell type is predominantly involved?
Show answer and explanation
Correct answer: B. Plasma cells
Multiple myeloma = malignant neoplasm of PLASMA CELLS (terminally differentiated B-lymphocytes). Accumulate in bone marrow, produce lytic lesions. Lab: Bence-Jones proteins, M-spike on serum electrophoresis, CRAB criteria (Calcium, Renal, Anemia, Bone lesions).