Pathology · single question

A small white lesion on the SOFT PALATE does not wipe off. All of the following are reasonable differential diagnoses EXCEPT:

  1. Nicotine stomatitis (smoker's palate)
  2. Hyperkeratosis
  3. Pleomorphic adenoma
  4. Squamous cell carcinoma
Show answer and explanation

Correct answer: C. Pleomorphic adenoma

  • A. Nicotine stomatitis appears as a white keratotic palatal change in smokers.
  • B. Frictional/idiopathic hyperkeratosis presents as a white patch.
  • C. Correct (the EXCEPTION). A pleomorphic adenoma is a submucosal SALIVARY mass, not a surface white plaque.
  • D. SCC can present as a non-wipeable white (leukoplakic) lesion.

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