Pathology · single question

Clinical case: patient with a blue macule on the labial or buccal mucosa that BLANCHES with compression. Diagnosis:

  1. Varix (venous varicosity)
  2. Amalgam tattoo (does NOT blanch)
  3. Melanoma
  4. Melanocytic nevus
Show answer and explanation

Correct answer: A. Varix (venous varicosity)

  • A. Correct. A blue/purple lesion that blanches with compression indicates a vascular lesion containing blood that can be displaced — characteristic of a varix.
  • B. An amalgam tattoo does NOT blanch with pressure, since it's caused by embedded metal particles rather than blood.
  • C. Melanoma is pigment-based (melanin), not blood-filled, and does not blanch with pressure; it also presents with more concerning features.
  • D. A melanocytic nevus is also pigment-based and does not blanch with pressure.

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