Pharmacology · single question

Buspirone is prescribed for which of the following conditions?

  1. Opioid withdrawal
  2. Acute psychosis
  3. Generalized anxiety disorder
  4. Bipolar depression
Show answer and explanation

Correct answer: C. Generalized anxiety disorder

  • A. Methadone, buprenorphine, or clonidine are used for opioid withdrawal, not buspirone.
  • B. Antipsychotics (e.g., haloperidol, olanzapine) treat acute psychosis; buspirone is not appropriate.
  • C. Correct. Buspirone is an anxiolytic (5-HT1A partial agonist) approved for generalized anxiety disorder (GAD). Unlike benzodiazepines, it is non-sedating, non-habit-forming, and has a delayed onset of 1–2 weeks.
  • D. Buspirone is not indicated for bipolar depression; mood stabilizers (lithium, valproate) and antidepressants are used.

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