Micro & Immunology · single question

Beyond its ability to form pseudohyphae, what additional mechanism contributes to Candida's persistence and resistance within the body?

  1. Biofilm formation
  2. Spore-forming capability identical to bacterial endospores
  3. Production of exotoxins identical to Clostridium species
  4. Gram-positive cell wall structure
Show answer and explanation

Correct answer: A. Biofilm formation

Candida species form robust biofilms — structured microbial communities encased in a protective extracellular matrix — on mucosal surfaces, dentures, and medical devices, significantly increasing resistance to antifungal agents and host immune clearance compared with free-floating (planktonic) cells. This is an important mechanism distinct from, and in addition to, Candida's well-known ability to switch between yeast and pseudohyphal/hyphal forms.

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