Micro & Immunology · single question

Mast cells are central to which type of hypersensitivity?

  1. Type I
  2. Type II
  3. Type III
  4. Type IV
Show answer and explanation

Correct answer: A. Type I

  • A. Correct. IgE-sensitized MAST cells degranulate (histamine, etc.) in Type I immediate hypersensitivity.
  • B. Incorrect. Type II is antibody (IgG/IgM)-mediated cytotoxicity.
  • C. Incorrect. Type III is immune-complex mediated.
  • D. Incorrect. Type IV is delayed, T-cell mediated.

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