Micro & Immunology · single question

What is the major immunoglobulin found in saliva, and what is its general functional role?

  1. Secretory IgA, providing combined antibacterial and antiviral mucosal defense by blocking pathogen adherence and aiding neutralization
  2. IgG, providing primarily antifungal defense
  3. IgM, providing primarily antiparasitic defense
  4. IgE, providing primarily anti-inflammatory defense
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Correct answer: A. Secretory IgA, providing combined antibacterial and antiviral mucosal defense by blocking pathogen adherence and aiding neutralization

Secretory IgA is the predominant immunoglobulin in saliva, produced by local plasma cells and transported across mucosal epithelium with a protective secretory component. It provides first-line mucosal immune defense with both antibacterial activity (blocking bacterial adherence to mucosal surfaces) and antiviral activity (neutralizing viral particles before they can infect host cells).

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