Pathology · single question

An autoimmune disorder featuring dry eyes (keratoconjunctivitis sicca) and dry mouth, often with positive anti-Ro/anti-La antibodies, is:

  1. Sjögren syndrome
  2. Systemic lupus erythematosus
  3. Scleroderma
  4. Rheumatoid arthritis
Show answer and explanation

Correct answer: A. Sjögren syndrome

  • A. Correct. Sjögren syndrome is lymphocytic destruction of exocrine glands producing the sicca complex (dry eyes and mouth).
  • B. SLE is a multisystem immune-complex disease, though it can overlap with Sjögren.
  • C. Scleroderma features skin/organ fibrosis.
  • D. RA primarily affects joints (and can be a secondary association).

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