Pathology · single question
A patient with a long history of betel nut (areca nut) chewing presents with a burning sensation, progressive trismus, and blanched, fibrous changes of the buccal mucosa. What is the most likely diagnosis?
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Correct answer: A. Oral submucous fibrosis (a progressive, potentially malignant fibrosing condition strongly linked to areca/betel nut chewing)
Oral submucous fibrosis is a chronic, progressive, potentially malignant condition strongly and specifically linked to areca nut/betel quid chewing, characterized by juxtaepithelial fibrosis causing blanching, stiffness, burning sensation, and progressive trismus as fibrous bands develop — most commonly affecting the buccal mucosa, retromolar area, and soft palate.