Pathology · single question
An 8-year-old female presents with bilateral enlarged cheeks; a panoramic radiograph reveals bilateral radiolucencies in the body of the mandible. What is the most likely diagnosis?
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Correct answer: A. Cherubism
Cherubism, an autosomal dominant fibro-osseous condition (SH3BP2 gene mutation), classically presents in children with bilateral, symmetric cheek/jaw enlargement and bilateral multilocular radiolucencies of the mandible (often described as a 'soap bubble' or 'cherub-like' facial appearance), frequently stabilizing or regressing after puberty.