Pathology · single question

A patient presents with hairy tongue. What is the best diagnostic method to confirm the causative organism?

  1. Excisional biopsy
  2. Incisional biopsy
  3. Culture and sensitivity
  4. Immunofluorescence
Show answer and explanation

Correct answer: C. Culture and sensitivity

  • A. Incorrect. Excisional biopsy is used for definitive removal of discrete lesions, not hairy tongue diagnosis.
  • B. Incorrect. Incisional biopsy is not first-line for hairy tongue, which has a distinct clinical appearance.
  • C. CORRECT. Hairy tongue (lingua villosa) is diagnosed clinically and confirmed with culture and sensitivity to identify the causative organism (most commonly Candida species or bacterial overgrowth). Culture guides targeted treatment selection.
  • D. Incorrect. Immunofluorescence is used for immune-mediated vesiculobullous conditions (pemphigus, lichen planus), not hairy tongue.

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