Pharmacology · single question
Amoxicillin can interact with all of the following EXCEPT:
Show answer and explanation
Correct answer: D. Analgesics (NSAIDs/acetaminophen)
- A. Amoxicillin can reduce the efficacy of oral contraceptives by altering gut flora and reducing enterohepatic circulation of estrogen.
- B. Amoxicillin can potentiate warfarin's anticoagulant effect by reducing vitamin K-producing gut bacteria, increasing bleeding risk.
- C. Amoxicillin can increase methotrexate toxicity by reducing renal excretion of methotrexate.
- D. Analgesics (NSAIDs and acetaminophen) do not have significant pharmacokinetic interactions with amoxicillin. They can be safely co-administered for dental pain management. ✓