Pharmacology · single question

What is the first-line treatment for symptomatic recurrent intraoral/oral herpetic lesions?

  1. A topical corticosteroid
  2. A systemic antiviral, such as valacyclovir or acyclovir
  3. An antibiotic
  4. An antifungal
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Correct answer: B. A systemic antiviral, such as valacyclovir or acyclovir

Systemic antivirals (valacyclovir, acyclovir, famciclovir) shorten the course and reduce severity of HSV outbreaks, ideally started at the earliest prodromal signs. Topical antivirals (e.g., acyclovir cream) have a more modest effect and are mainly used for perioral/lip lesions.

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