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Pharmacology · single question

A woman on estradiol needs an extraction. All of the following regarding antibiotics are TRUE EXCEPT:

  1. Antibiotics may reduce contraceptive effectiveness
  2. Antibiotics can cause GI disturbances
  3. Antibiotics interfere with analgesics
  4. Antibiotics can cause allergic reactions
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Correct answer: C. Antibiotics interfere with analgesics

  • A. True (not the exception). Some antibiotics can reduce hormonal contraceptive efficacy (most clearly the enzyme-inducer rifampin); patients are advised to use backup contraception.
  • B. True (not the exception). GI upset (nausea, diarrhea) is a common antibiotic side effect.
  • C. Correct — this is the EXCEPTION (false). Antibiotics do not characteristically 'interfere with' analgesics like acetaminophen/ibuprofen in a clinically meaningful way.
  • D. True (not the exception). Allergic/hypersensitivity reactions (e.g., to penicillins) are well recognized.

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