Medical Emergencies · single question

A pregnant patient presents with right upper quadrant pain after fatty meals and is found to have gallstones. What is the most likely diagnosis?

  1. Appendicitis
  2. Cholecystitis
  3. Peptic ulcer disease
  4. Pancreatitis
Show answer and explanation

Correct answer: B. Cholecystitis

  • A. APPENDICITIS causes RIGHT LOWER quadrant pain at McBurney point, though the appendix is displaced upward in later pregnancy — but it is not associated with gallstones or fatty-food intolerance.
  • B. CORRECT. Gallstones plus right upper quadrant pain provoked by fatty food is CHOLECYSTITIS (inflammation of the gallbladder secondary to cystic duct obstruction by a stone). Pregnancy markedly increases risk: oestrogen raises biliary cholesterol saturation while progesterone reduces gallbladder motility, so bile stasis and stone formation are both promoted. Look for Murphy sign, fever and leucocytosis.
  • C. PEPTIC ULCER DISEASE gives epigastric pain related to meals and is linked to H. pylori and NSAIDs, not to gallstones.
  • D. PANCREATITIS can certainly be caused by gallstones and is an important complication, but it produces severe EPIGASTRIC pain radiating to the BACK with raised lipase — not the described right upper quadrant fatty-food pattern.

Note: Dental relevance: defer elective care during an acute episode, and be aware that severe vomiting from biliary colic or hyperemesis causes PERIMYLOLYSIS — erosion of the palatal surfaces of the upper anterior teeth. Advise rinsing with water or sodium bicarbonate rather than brushing immediately after vomiting.

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