Pediatric Dentistry · single question
A patient with Type 2 diabetes mellitus presents for dental care. Which metabolic explanation BEST describes Type 2 DM?
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Correct answer: D. Most obese people suffer from peripheral insulin resistance (Type 2 DM)
- A. Absolute insulin deficiency is characteristic of Type 1 DM where beta cells are destroyed.
- B. Autoimmune destruction of beta cells describes TYPE 1 DM — NOT Type 2.
- C. MODY (maturity-onset diabetes of the young) is a monogenic form of diabetes caused by specific gene mutations — not the standard Type 2 DM description.
- D. Correct. Type 2 DM is characterized by peripheral insulin resistance combined with relative (not absolute) insulin deficiency. Obesity is the primary risk factor — excess adipose tissue causes insulin resistance. Pancreatic beta cells initially compensate by producing more insulin but eventually fail.
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