A patient with rheumatoid arthritis treated with methotrexate is most at risk for which dentally relevant concern?

Methotrexate is immunosuppressive, increasing infection risk and impairing healing; it can also cause oral ulcerations and (with antiresorptive co-therapy) raise osteonecrosis concern.Other options: It does not accelerate eruption, cause enamel hyperplasia, or increase salivation.Key exam takeaway: Methotrexate = immunosuppression: higher infection risk, mucosal ulceration, impaired healing.