Pharmacology · single question

A patient with mitral valve prolapse (a condition no longer requiring prophylaxis) who is allergic to penicillin needs care. If antibiotic prophylaxis were indicated, what would be appropriate?

  1. Amoxicillin 2 g, 60 minutes before treatment
  2. Doxycycline 200 mg, 60 minutes before treatment
  3. Clindamycin (or azithromycin/cephalexin) for penicillin-allergic patients when prophylaxis is indicated
  4. No prophylaxis is needed
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Correct answer: D. No prophylaxis is needed

Mitral valve prolapse is NOT among the cardiac conditions requiring antibiotic prophylaxis under current AHA guidelines, so no prophylaxis is indicated regardless of penicillin allergy.Other options: Amoxicillin is contraindicated by the penicillin allergy; doxycycline is not a standard prophylactic regimen; clindamycin would be the penicillin-allergy alternative only if prophylaxis were indicated, which it is not here.Key exam takeaway: Prophylaxis is reserved for specific high-risk cardiac conditions (prosthetic valves, prior IE, certain congenital defects, transplant valvulopathy). MVP does not qualify.

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