Periodontics · single question

A patient with localized periodontitis requires adjunctive pharmacological treatment. The most appropriate locally delivered antibiotic is:

  1. Minocycline microspheres (Arestin)
  2. Metronidazole
  3. Tetracycline fibers
  4. Chlorhexidine chip (PerioChip)
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Correct answer: A. Minocycline microspheres (Arestin)

  • A. ✅ Correct. Minocycline microspheres (Arestin) is the locally delivered antibiotic specifically indicated as an adjunct to SRP in localized periodontitis. It provides sustained-release minocycline directly in the periodontal pocket.
  • B. ❌ Metronidazole is used systemically for periodontitis, not as a standard local delivery system.
  • C. ❌ Tetracycline fibers (Actisite) are an older system and Arestin is the current preferred option.
  • D. ❌ Chlorhexidine chips are an ANTISEPTIC (not antibiotic) adjunct — Arestin is the antibiotic-specific answer.

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