Pathology · single question

A patient with Bell's palsy (confirmed LMN lesion, unable to close eye) presents within 72 hours of onset. What is the MOST important medication to prescribe?

  1. Antiviral medication (e.g., acyclovir or valacyclovir)
  2. Antibiotics
  3. Antiviral + systemic corticosteroids combined
  4. Systemic corticosteroids (e.g., prednisone)
Show answer and explanation

Correct answer: A. Antiviral medication (e.g., acyclovir or valacyclovir)

  • A. CORRECT. Per current evidence (AAO-HNS guidelines), if Bell's palsy is treated within 72 hours of onset, the PRIMARY medication is oral corticosteroids (prednisone). Antivirals (valacyclovir) are often added given the presumed HSV-1 reactivation etiology, though evidence for antivirals alone is weaker. Combined therapy (steroid + antiviral) within 72h of onset has the best outcomes for complete recovery. The question asks for the MOST important: antiviral + corticosteroid = best current practice.
  • B. Antibiotics are not indicated for Bell's palsy — it is a viral/idiopathic condition, not bacterial.
  • C. COMBINED antiviral + corticosteroids is the best evidence-based treatment when initiated within 72 hours — this is the most appropriate answer.
  • D. Corticosteroids alone (without antiviral) are the minimum evidence-based treatment. Most guidelines recommend combined therapy for optimal outcomes.

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