Pathology · single question

A nodular lesion clinically resembling a fibroma on the lateral tongue – which is NOT in its differential diagnosis (the EXCEPTION)?

  1. Granular cell tumor
  2. Schwannoma
  3. Verruca (verruca vulgaris)
  4. Traumatic fibroma
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Correct answer: C. Verruca (verruca vulgaris)

  • A. Incorrect – a classic firm dorsal/lateral tongue nodule in the DDx.
  • B. Incorrect – a smooth submucosal nerve-sheath nodule that can mimic a fibroma.
  • C. Correct (the EXCEPTION) – a verruca is a papillary, rough/exophytic surface lesion, not a smooth submucosal nodule, so it does not belong in the DDx of a fibroma-like nodule.
  • D. Incorrect – it IS the lesion being mimicked, so clearly part of the DDx.

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