Pharmacology · single question

A patient reports a history of methamphetamine use. What is the main effect of methamphetamine on the body?

  1. Increase in acetylcholine release
  2. Increase in dopamine release
  3. Decrease in serotonin activity
  4. Inhibition of norepinephrine release
Show answer and explanation

Correct answer: B. Increase in dopamine release

  • A. Methamphetamine's primary action is on catecholamines, not acetylcholine.
  • B. Correct. Methamphetamine is a potent stimulant that markedly increases release of dopamine (and norepinephrine), driving its euphoric and sympathomimetic effects.
  • C. It increases monoamine activity rather than decreasing serotonin.
  • D. It increases (not inhibits) norepinephrine release.

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