Pediatric Dentistry · single question

A patient presents with multiple skin pigmentation, lethargy, and low blood pressure (80/60 mmHg) with bronze skin discoloration. What is the most likely diagnosis?

  1. Hypothyroidism
  2. Cushing's syndrome
  3. Crohn's disease
  4. Addison's disease
Show answer and explanation

Correct answer: D. Addison's disease

  • A. Hypothyroidism causes fatigue, weight gain, cold intolerance, and dry skin — not hypotension with bronze pigmentation.
  • B. Cushing's syndrome causes the OPPOSITE: hypertension, moon face, central obesity, purple striae, and hyperpigmentation (in ACTH-dependent Cushing's).
  • C. Crohn's disease (inflammatory bowel disease) causes GI symptoms; it does not cause hypotension and bronze pigmentation.
  • D. Correct. Addison's disease (primary adrenal insufficiency) classically presents with hypotension, weakness/lethargy, and HYPERPIGMENTATION (bronze skin) due to excess ACTH stimulating melanocytes. Low cortisol causes low blood pressure and electrolyte imbalances.

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