Pediatric Dentistry · single question

Cleidocranial dysplasia — multiple unerupted permanent and supernumerary teeth.

  1. Crouzon syndrome
  2. Gardner syndrome
  3. Cleidocranial dysplasia
  4. Down syndrome
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Correct answer: C. Cleidocranial dysplasia

Cleidocranial dysplasia is autosomal dominant (RUNX2 mutation). Hallmark features: hypoplastic/absent clavicles, delayed closure of cranial sutures, frontal bossing, multiple supernumerary teeth, retained primary teeth, and delayed eruption of permanent teeth. Gardner syndrome also has supernumerary teeth and osteomas but lacks the clavicular defect.

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