Pharmacology · single question
A patient is taking multiple medications. Which of the following is a proton pump inhibitor (PPI)?
Show answer and explanation
Correct answer: B. Omeprazole
- A. Ranitidine is an H2 receptor antagonist, not a PPI. H2 blockers work differently from PPIs.
- B. Omeprazole (Prilosec) is a classic PPI — it irreversibly inhibits the H+/K+ ATPase pump in gastric parietal cells, reducing acid secretion.
- C. Metoclopramide is a prokinetic agent and dopamine antagonist, not a PPI.
- D. Sucralfate is a cytoprotective agent that coats the gastric mucosa — it is not a PPI.