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Pharmacology · single question

A patient is on clopidogrel and aspirin. What dental treatment modifications are needed?

  1. No modifications needed
  2. Use general anesthesia to avoid bleeding
  3. Stop clopidogrel 5 days before treatment
  4. Consult physician and check INR before treatment
Show answer and explanation

Correct answer: A. No modifications needed

  • A. Current ADA guidelines support performing most dental procedures WITHOUT stopping aspirin or clopidogrel. The risk of a thromboembolic event (MI or stroke) from stopping medication FAR outweighs the risk of minor increased bleeding that can be managed with local hemostatic measures (pressure, sutures, hemostatic agents).
  • B. General anesthesia is not indicated simply because a patient is on antiplatelet therapy. Local hemostatic measures are far safer and more appropriate.
  • C. Stopping antiplatelet therapy increases risk of stent thrombosis, MI, or stroke — the risk does NOT outweigh the benefit for routine dental procedures.
  • D. INR is used for warfarin monitoring — NOT for antiplatelet therapy. Clopidogrel and aspirin do not affect INR.

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