Pathology · single question
A patient presents with a description consistent with Civatte bodies on histologic examination. What medication is most appropriate?
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Correct answer: A. Clobetasol
- A. Civatte bodies (colloid bodies/cytoid bodies) are apoptotic keratinocytes seen in oral LICHEN PLANUS. Lichen planus is treated with TOPICAL CORTICOSTEROIDS — clobetasol propionate (high-potency topical steroid) is the first-line treatment for symptomatic oral lichen planus.
- B. Acyclovir is an antiviral — used for herpetic infections, not lichen planus.
- C. Clotrimazole is an antifungal — used for candidiasis, not lichen planus.
- D. Amoxicillin is a penicillin antibiotic — not indicated for lichen planus.