Pathology · single question

A malar ('butterfly') rash across the cheeks and nasal bridge, sparing the nasolabial folds, is classically associated with which condition?

  1. Systemic lupus erythematosus (SLE)
  2. Rheumatoid arthritis
  3. Sjögren's syndrome
  4. Sarcoidosis
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Correct answer: A. Systemic lupus erythematosus (SLE)

The malar/butterfly rash — erythema across both cheeks and the nasal bridge, characteristically sparing the nasolabial folds — is one of the classic diagnostic criteria for systemic lupus erythematosus (SLE), an autoimmune connective tissue disease that can also cause oral ulcerations and discoid lesions.

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