Pathology · single question

Gorlin (nevoid basal cell carcinoma) syndrome is associated with all of the following EXCEPT:

  1. Hypodontia (congenitally missing teeth)
  2. Multiple odontogenic keratocysts
  3. Basal cell carcinomas of the skin
  4. Calcification of the falx cerebri
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Correct answer: A. Hypodontia (congenitally missing teeth)

Gorlin syndrome classically features multiple odontogenic keratocysts, multiple basal cell carcinomas, and calcification of the falx cerebri (along with rib anomalies and frontal bossing). Hypodontia is not a feature.Other options: OKCs, basal cell carcinomas, and falx calcification are core diagnostic features of the syndrome.Key exam takeaway: Gorlin syndrome triad: multiple OKCs, basal cell carcinomas, and falx cerebri calcification.

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