Pharmacology · single question

A hypertensive patient takes metoprolol. Mechanism of action of this antihypertensive?

  1. Increases nitric oxide release
  2. Blocks calcium channels
  3. Competitively inhibits β1 receptors
  4. Competitively inhibits β2 receptors
Show answer and explanation

Correct answer: C. Competitively inhibits β1 receptors

  • A. Incorrect. That describes nitrates/some vasodilators, not metoprolol.
  • B. Incorrect. Calcium-channel blockade describes drugs like amlodipine.
  • C. Correct. Metoprolol is a cardioselective (β1) beta blocker, lowering heart rate and cardiac output to reduce blood pressure.
  • D. Incorrect. β2 blockade would risk bronchospasm; metoprolol is selective for β1 (important in this asthmatic patient).

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