Pharmacology · single question
What is the mechanism of action of adalimumab (Humira)?
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Correct answer: A. Tumor necrosis factor-alpha (TNF-alpha) inhibitor
Adalimumab is a monoclonal antibody that binds and neutralizes TNF-alpha, reducing inflammation in rheumatoid arthritis, Crohn disease, and psoriasis.Other options: IL-6 receptor blockade describes tocilizumab; CD20 depletion describes rituximab; calcineurin inhibition describes cyclosporine/tacrolimus.Key exam takeaway: Humira (adalimumab) = anti-TNF-alpha monoclonal antibody.
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