Pathology · single question
What is the most common malignancy seen as a complication of AIDS?
Show answer and explanation
Correct answer: B. Kaposi sarcoma
- A. Neurofibromas are benign nerve sheath tumors associated with neurofibromatosis — not specifically AIDS-related.
- B. Kaposi sarcoma (KS) is the MOST COMMON AIDS-defining malignancy. Caused by Human Herpesvirus 8 (HHV-8/KSHV), KS appears as purple/red-brown vascular lesions on skin, mucous membranes (palate, gingiva), and visceral organs. It is pathognomonic of AIDS and was the first AIDS-defining neoplasm recognized.
- C. Liposarcoma is a malignant soft tissue tumor — not specifically AIDS-related.
- D. Fibrosarcoma is not an AIDS-defining malignancy.