Pathology · single question

A 28-year-old male presents with unilateral facial crusting ulcers, limited facial muscle mobility, and tinnitus on the same side. The MOST likely diagnosis and nerve involved are:

  1. Trigeminal neuralgia — trigeminal nerve (CN V)
  2. Herpes labialis — trigeminal nerve (V1)
  3. Ramsay Hunt syndrome — facial nerve (CN VII, geniculate ganglion VZV reactivation)
  4. Bell's palsy — facial nerve (idiopathic)
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Correct answer: C. Ramsay Hunt syndrome — facial nerve (CN VII, geniculate ganglion VZV reactivation)

  • A. Trigeminal neuralgia causes sharp lancinating facial pain (not paralysis), and has no vesicular rash or auditory symptoms.
  • B. Herpes labialis (cold sores) involves VZV reactivation at the lips — it does not cause facial paralysis or tinnitus.
  • C. Correct. Ramsay Hunt syndrome (herpes zoster oticus) is caused by reactivation of varicella-zoster virus (VZV) in the geniculate ganglion of the facial nerve (CN VII). Classic triad: (1) painful vesicular rash on the ear/face, (2) ipsilateral facial muscle paralysis, (3) auditory symptoms (tinnitus, hearing loss, vertigo). Treatment is acyclovir + prednisone.
  • D. Bell's palsy is idiopathic facial nerve palsy WITHOUT the vesicular rash or auditory symptoms described here.

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