Pathology · single question

A patient has preauricular crepitus (crackling at the TMJ) but NO pain. Rheumatoid factor is NEGATIVE. What is the MOST likely diagnosis?

  1. Rheumatoid arthritis
  2. Osteoarthritis
  3. Gout arthritis
  4. Psoriatic arthritis
Show answer and explanation

Correct answer: B. Osteoarthritis

  • A. Incorrect. Rheumatoid arthritis is ruled out by the NEGATIVE rheumatoid factor (RF). Also, RA is a bilateral, systemic autoimmune disease — not typically presenting as isolated TMJ crepitus with negative RF.
  • B. Correct. Painless preauricular crepitus with negative RF in a patient (especially middle-aged/older) is classic OSTEOARTHRITIS (OA) of the TMJ. OA involves progressive degradation of articular cartilage → bone-on-bone contact → crepitus. RF is negative in OA (unlike RA). The absence of pain at this stage is common in early-to-moderate TMJ OA.
  • C. Incorrect. Gout arthritis affects the TMJ rarely and presents with acute pain, redness, and tophi — not painless crepitus.
  • D. Incorrect. Psoriatic arthritis may affect the TMJ but is associated with a history of psoriasis and is less common than OA.

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