Medical Emergencies · single question

Which statement about rheumatoid arthritis (RA) is NOT TRUE?

  1. RA can be triggered by Streptococcal pharyngitis (throat infection)
  2. RA is an autoimmune condition affecting joints
  3. RA can be triggered by Epstein-Barr virus/mononucleosis
  4. RA can cause TMJ involvement and limited mouth opening
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Correct answer: C. RA can be triggered by Epstein-Barr virus/mononucleosis

  • A. Group A Streptococcal infection has been associated with triggering autoimmune conditions — this has some support in literature for RA.
  • B. RA is indeed an autoimmune condition — this is TRUE.
  • C. Correct — this is the NOT TRUE statement. EBV/mononucleosis has been proposed as a potential trigger for some autoimmune conditions, but the DIRECT causal link between mononucleosis and RA is not established as a proven trigger in the same way as other RA risk factors (genetic, Strep infection, other triggers). The source specifically flagged this as 'not sure if true' — the board answer is that EBV/mono is NOT a recognized established RA trigger.
  • D. TMJ involvement causing limited opening is a recognized feature of RA — TRUE.

Note: This question is flagged as clinically nuanced. The study group should verify: while EBV is discussed in autoimmunity research, it is not a classically established RA trigger on INBDE. Streptococcal throat infection IS associated with some autoimmune conditions.

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