Medical Emergencies · single question

Osteomalacia (defective bone mineralization, often due to vitamin D deficiency) is characterized by which laboratory finding?

  1. Elevated serum alkaline phosphatase
  2. Decreased serum alkaline phosphatase
  3. Decreased serum calcium with no change in alkaline phosphatase
  4. No characteristic laboratory abnormalities
Show answer and explanation

Correct answer: A. Elevated serum alkaline phosphatase

Osteomalacia is associated with elevated serum alkaline phosphatase, reflecting increased osteoblastic activity as bone attempts to compensate for the underlying defective mineralization — a finding shared with other high-bone-turnover conditions.

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