Pathology · patient case question

Which peripheral blood change is most characteristic of an ACUTE dentoalveolar abscess in an otherwise healthy patient?

Patient case: Patient with leukaemia presenting with oral infection

Patient: Adult with a recent diagnosis of leukaemia

Chief complaint: Recurrent mouth infections and sore gums.

Background: Undergoing haematological workup. No radiotherapy to the head and neck.

Current findings: Generalised gingival inflammation and a poorly localised soft tissue infection.

  1. Leukocytosis with neutrophil predominance
  2. Neutropenia
  3. Lymphocytosis
  4. Leukopenia
Show answer and explanation

Correct answer: A. Leukocytosis with neutrophil predominance

  • A. CORRECT. A pyogenic bacterial infection drives neutrophils out of the marrow, producing LEUKOCYTOSIS, typically 12,000–20,000/mm³ with a left shift. The neutrophils constitute the pus itself.
  • B. Neutropenia predisposes TO severe infection rather than resulting from one.
  • C. Lymphocytosis is the pattern of viral and certain chronic infections.
  • D. Leukopenia signals marrow failure or overwhelming sepsis — an ominous finding requiring urgent medical referral.

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