Pathology · single question
Which oral finding in this patient is MOST likely due to amyloidosis associated with multiple myeloma?
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Correct answer: B. Macroglossia with tongue scalloping
AL amyloidosis (immunoglobulin light chain) is the most common amyloid type in multiple myeloma. Deposition in the tongue produces macroglossia with lateral scalloping from pressure against the teeth. Other oral findings include waxy papules, submucosal hemorrhage, and xerostomia. Biopsy stained with Congo red shows apple-green birefringence under polarized light.