Pathology · single question
A patient's lab shows elevated SSA (anti-Ro) antibodies. Most consistent diagnosis?
Show answer and explanation
Correct answer: A. Sjogren's syndrome
Anti-SSA (Ro) antibodies are most strongly associated with PRIMARY SJOGREN'S syndrome (also seen in SLE). In Sjogren's, both SSA and SSB (anti-La) antibodies are characteristic. RA = anti-CCP and RF. Scleroderma = anti-Scl-70 and anti-centromere.