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Pharmacology · single question

Which of the following opioids is classified as FULLY SYNTHETIC?

  1. Hydromorphone
  2. Oxycodone
  3. Buprenorphine
  4. Fentanyl
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Correct answer: D. Fentanyl

Fentanyl is fully synthetic — entirely man-made with no plant-derived precursors. Fully synthetic opioids: fentanyl, meperidine, tramadol, methadone, alfentanil.
  • A. Hydromorphone = SEMI-SYNTHETIC (from morphine).
  • B. Oxycodone = SEMI-SYNTHETIC (from thebaine).
  • C. Buprenorphine = SEMI-SYNTHETIC (from thebaine) — used for pain and opioid use disorder.
  • D. CORRECT. Fentanyl = fully synthetic opioid. Lab-created. ~100x more potent than morphine.

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