Pharmacology · single question

Drug-induced gingival enlargement most commonly affects which area of the gingiva?

  1. Mucogingival junction
  2. Free gingival margin and interdental papillae
  3. Attached gingiva only
  4. Alveolar mucosa
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Correct answer: B. Free gingival margin and interdental papillae

Drug-induced gingival enlargement (DIGE) typically begins in the interdental papillae and the free gingival margin, and in severe cases may extend to cover the clinical crowns of the teeth. The anterior facial gingiva is most commonly affected. The enlargement involves both the free gingiva and the attached gingiva in advanced cases. Pure DIGE has a fibrotic, firm, pale pink appearance, while enlargement exacerbated by inflammation appears redder and bleeds more easily. The mucogingival junction and alveolar mucosa are generally not primarily involved.

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