Micro & Immunology · single question
Which of the following is a Type III (immune complex–mediated) hypersensitivity reaction?
Show answer and explanation
Correct answer: B. Systemic lupus erythematosus (SLE)
- A. Erythroblastosis fetalis (hemolytic disease of the newborn) is Type II (antibody-mediated cytotoxicity via anti-Rh IgG).
- B. SLE is the classic Type III example. Antigen-antibody immune complexes deposit in tissues (kidney, skin, joints) and activate complement, causing inflammation.
- C. Contact dermatitis is Type IV (cell-mediated / delayed-type hypersensitivity, T-cell dependent).
- D. Graves disease is Type II (antibody-mediated: stimulatory autoantibodies against TSH receptor).
Practice Micro & Immunology questions Micro & Immunology study notes