Micro & Immunology · single question

Which cell type is found in increased numbers in the bone marrow of a patient with multiple myeloma?

  1. Plasma cells (multiple myeloma is a malignancy of plasma cells)
  2. Eosinophils
  3. Neutrophils
  4. Lymphocytes generally, without plasma cell predominance
Show answer and explanation

Correct answer: A. Plasma cells (multiple myeloma is a malignancy of plasma cells)

Multiple myeloma is a malignant proliferation of plasma cells within the bone marrow, leading to monoclonal antibody (M-protein) overproduction, bone destruction (including characteristic 'punched-out' radiolucent lesions, sometimes seen in the jaws), anemia, renal impairment, and hypercalcemia.

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