Anatomy & Histology · single question

Which of the following about cartilage growth is INCORRECT (the exception)?

  1. Cartilage grows by intramembranous ossification
  2. Cartilage can grow by appositional growth (from perichondrium)
  3. Cartilage can grow by interstitial growth (from within)
  4. Cartilage resists direct compression better than bone
Show answer and explanation

Correct answer: A. Cartilage grows by intramembranous ossification

  • A. Correct — this is the EXCEPTION. Cartilage does NOT grow by INTRAMEMBRANOUS ossification. Intramembranous ossification describes how BONE forms directly from mesenchymal connective tissue (e.g., flat bones of the skull). Cartilage forms through CHONDROGENESIS. Bone replaces cartilage through ENDOCHONDRAL ossification — but cartilage itself does not undergo intramembranous ossification.
  • B. Incorrect — this IS true. Cartilage can also grow by APPOSITIONAL growth (new cartilage added from the perichondrium on the outer surface).
  • C. Incorrect — this IS true. Cartilage can grow by INTERSTITIAL growth (chondrocytes divide within the matrix, expanding the cartilage from within). Unique to cartilage — cannot occur in bone.
  • D. Incorrect — this IS true. Cartilage resists compressive forces well due to its hydrated matrix containing proteoglycans.

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