Pharmacology · single question
Which laboratory test should be monitored in a patient on methotrexate (and a TNF inhibitor)?
Show answer and explanation
Correct answer: A. Renal function (creatinine/creatinine clearance) — and liver/CBC
- A. Correct. Methotrexate is renally cleared and hepatotoxic/myelosuppressive, so creatinine clearance, liver enzymes, and CBC are monitored.
- B. Glucose is not the key methotrexate-monitoring test.
- C. Thyroid studies are unrelated to methotrexate safety.
- D. Amylase is not part of methotrexate monitoring.