Pharmacology · single question
Carbamazepine is used for trigeminal neuralgia. Its mechanism of action is:
Show answer and explanation
Correct answer: C. Sodium channel blocker
- A. GABA receptor agonism describes benzodiazepines and barbiturates, not carbamazepine.
- B. Potassium channel blockers are used in a different pharmacological context (e.g., some cardiac arrhythmias); not the mechanism of carbamazepine.
- C. Correct. Carbamazepine blocks voltage-gated sodium channels, stabilizing neuronal membranes and reducing repetitive firing. This is the basis for its anticonvulsant and analgesic effects in trigeminal neuralgia.
- D. T-type calcium channel blockers (e.g., ethosuximide) are used for absence seizures — not carbamazepine's mechanism.