Micro & Immunology · single question

Which immunoglobulin mediates the humoral (type I hypersensitivity) response in allergies?

  1. IgA
  2. IgE
  3. IgM
  4. IgG
Show answer and explanation

Correct answer: B. IgE

  • A. Incorrect – mucosal/secretory antibody.
  • B. Correct – IgE binds mast cells/basophils and triggers degranulation in allergic (type I) hypersensitivity.
  • C. Incorrect – the first antibody of a PRIMARY response, not the allergy mediator.
  • D. Incorrect – main antibody of the secondary response/opsonization, not allergy.

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