Micro & Immunology · single question
Which immunoglobulin is predominantly found in the gingival crevicular fluid (GCF)?
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Correct answer: C. IgG
- A. Incorrect. IgM is the first antibody produced in primary immune response — it is present in GCF but not the predominant type.
- B. Incorrect. IgE is associated with immediate hypersensitivity (Type I) reactions — not a significant component of GCF.
- C. Correct. IgG is the predominant immunoglobulin found in GINGIVAL CREVICULAR FLUID. GCF is essentially a transudate/exudate of serum, and IgG is the most abundant serum immunoglobulin. IgG levels in GCF increase significantly with periodontal inflammation.
- D. Incorrect. IgA is the predominant immunoglobulin in SALIVA (as secretory IgA), not in GCF.
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