Pharmacology · single question
Which drug combination is most associated with the risk of rhabdomyolysis?
Show answer and explanation
Correct answer: B. A statin (e.g., simvastatin) + fluconazole
- A. Dual antiplatelet therapy raises bleeding risk, not rhabdomyolysis.
- B. Correct. Azole antifungals (fluconazole) inhibit statin metabolism (CYP), raising statin levels and rhabdomyolysis risk.
- C. This antihypertensive combo isn't linked to rhabdomyolysis.
- D. This rate-control combo can cause bradycardia, not rhabdomyolysis.