Pharmacology · single question

Which of the following is NOT a typical effect of amphetamine use?

  1. Xerostomia
  2. Bradycardia and hypothermia
  3. Agitation and anxiety
  4. Tachycardia and hypertension
Show answer and explanation

Correct answer: B. Bradycardia and hypothermia

  • A. Xerostomia IS characteristic and is a major driver of 'meth mouth' — rampant, rapidly progressing caries on smooth and cervical surfaces, worsened by high-sugar drinks, bruxism, and poor hygiene.
  • B. CORRECT — this is NOT typical. Amphetamines are SYMPATHOMIMETIC stimulants; they produce TACHYCARDIA and HYPERTHERMIA, not bradycardia and hypothermia. Severe hyperthermia is in fact one of the life-threatening manifestations of amphetamine toxicity.
  • C. Agitation, anxiety, paranoia, and psychosis ARE characteristic and complicate behavior management.
  • D. Tachycardia, hypertension, and arrhythmia ARE characteristic and are the reason to AVOID epinephrine-containing local anesthetic within 24 hours of use.

Note: ⚠️ The recall keys 'fever' as the exception — that is wrong. Amphetamines cause HYPERthermia. Never give a vasoconstrictor to a patient who has used amphetamine or cocaine in the past 24 hours.

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